Paul Terry's Mighty Mouse Comics #59

Oil Can Harry hangs Pearl Pureheart off the Leaning Tower of Pisa by a single strand of spaghetti, while Mighty Mouse fights thousands upon thousands of lions in the remains of the Roman Coliseum. Harry drains the canals of Venice and reignites Mt. Vesuvius in his efforts to stop Mighty Mouse but ends up getting blasted into the stratosphere by a scalding burst of steam.