Kurt Busiek's Astro City #21

Comic-book writer Sally Twinings tries to keep up with the best-selling (but often unethical) comic-book publisher Manny Monkton. After being assaulted too often by superbeings that he has either cheated or insulted, Manny transforms his line to deal solely with cosmic beings on the theory that his comics will be far beneath their notice. This works well until the morning that his entire building disappears, with Manny inside. Sally decides to stick to mainstream publishers.